ea0037ep89 | Adrenal cortex | ECE2015
Dennedy Michael Conall
, Anamalai Anand K
, Smith Olivia Prankerd
, Powlson Andrew S
, Graggaber Johann
, Shaw Ashley
, Halsall David J
, Gurnell Mark
Subclinical hypercortisolism (SH) occurs in 530% of incidentally-detected adrenal adenomas (AIs). Common screening tests for ACTH-independent hypercortisolism have significant false positive rates, mandating further investigations that are both time and resource intensive. We investigated whether a low basal DHEAS level is a sensitive and specific screening test for the detection/exclusion of SH in patients with newly-diagnosed AI. We recruited 185 consecutive patients w...