Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep89 | Adrenal cortex | ECE2015

Low DHEAS: a sensitive and specific screening test for the detection of subclinical hypercortisolism in adrenal incidentalomas

Dennedy Michael Conall , Anamalai Anand K , Smith Olivia Prankerd , Powlson Andrew S , Graggaber Johann , Shaw Ashley , Halsall David J , Gurnell Mark

Subclinical hypercortisolism (SH) occurs in 5–30% of incidentally-detected adrenal adenomas (AIs). Common screening tests for ACTH-independent hypercortisolism have significant false positive rates, mandating further investigations that are both time and resource intensive. We investigated whether a low basal DHEAS level is a sensitive and specific screening test for the detection/exclusion of SH in patients with newly-diagnosed AI. We recruited 185 consecutive patients w...